Found a pretty nice one, Galaxy Online. Colonize planets, collect resources, research and design ships, assemble huge fleets (thousands of ships in a large one), and pew-pew pirates or enemy players.
Only real downside (besides the fact that it's an MMO) is that COMBAT IS FULLY AUTOMATED - there is nothing you can do to influence the outcome of a battle other than bringing better ships to begin with and maybe tweaking targeting settings.
Still, it's not all bad - fleet organization and design is very important. Having supplies is especially crucial - not much use in having the most powerful ships in the universe if they're out of fuel and ammo, is there?
Free to play, though you can buy some temporary and a couple of permanent boosts with money. Not much in the way of graphics, but it's a pretty nice game for the macro-minded. I'd strongly recommend giving it a try.
